Cholesterol and the effects of treatment
Cholesterol is a flat, waxy molecule is synthesized by all animals, including humans. It is one of the biochemical misunderstandings were discovered, and the mainstream media is certainly not helping the public understand the functions of cholesterol are in reality. Cholesterol has two main functions. The first is to serve as raw material or component, for all steroid hormone synthesis in the body. Hormones Steroids are very important molecules in the body that help the body to stress, the bone health, sexual health, regulation of the salt and many other functions. The second cholesterol main function is to provide the fluidity of cell membranes of the body, so they can work properly on their surfaces. Most cells rigid body are not: they are flexible, and flexibility are often related to its particular function. Without cholesterol to help maintain cell membranes fluid, most cells could not perform many of its basic functions, and would soon die as a result.
Cholesterol is a very important molecule, absolutely essential to life and health. In fat, cholesterol, too little can lead to increased suicides and the risk of cancer (1). Moreover, although levels normal cholesterol are to provide positive role in the body, too high cholesterol levels can be harmful to the heart and the rest of the cardiovascular system. High cholesterol can also contribute to hypertension, gallstones, mental problems, and impotence (2). Cholesterol has often been criticized as one of the main causes of many chronic diseases such as heart disease. However, cholesterol consumption has remained steady over the past 100 years, heart disease, but increased dramatically (1). Therefore, cholesterol intake alone can not be responsible for the increase in disease the heart. Much the reason is that for the average person, only 20% of blood cholesterol comes from eating animal products in their food, and the remaining 80% made of liver (3). The main dietary sources of cholesterol are eggs, meat and dairy products. As Dr. Udo Erasmus, an internationally recognized expert in the metabolism of fat, most people can control their levels of cholesterol in the diet alone (1).
Since cholesterol is a molecule of wax, not can dissolve in the blood, which is mostly water. It's like oil and salad dressing: oil and vinegar do not mix, because vinegar is mostly water. This is because molecules attract water more responsibly. Since the oils are usually not charged at all, can not draw water and do not penetrate the blood for themselves. Because of this problem, special proteins required for cholesterol in the blood of the shuttle to its various destinations in the body. Cholesterol, which is a form of fat and protein transport cholesterol are called lipoproteins. Different high-density lipoprotein, based on the amount of fat is linked to proteins. lipoprotein low density (LDL) carry cholesterol in the blood where it is needed. high density lipoprotein cholesterol (HDL), and then try to wipe off any excess cholesterol. HDL is known as when the "good" cholesterol because it regulates the rate of LDL cholesterol. excess cholesterol is carried to the liver by HDL and then broken and excreted.
When low levels of HDL, LDL is too high or there are not enough antioxidants to protect blood cholesterol, may end up sticking to the surfaces of pressure. In fact, one uses for cholesterol in the body is to help repair damage to certain tissues. Unless it has oxidized cholesterol is actually more useful for the organism that is harmful. If cholesterol becomes oxidized and adhere to the arterial wall, immune cells called macrophages, then come to clean the oxidized cholesterol. If there is a large amount of cholesterol oxidized in an area, macrophage cholesterol is to be extended damaged to die, and is now part of the blood of deposit, called plaque. plaque that accumulates can restrict blood flow to the heart, This can cause many serious diseases next.
Most health professionals recommend that LDL levels below 130 mg / dl (milligrams per deciliter). To help visualize an LDL of 130 mg / dl, you might think that this is 130 parts in 100,000, or 1.3 per thousand (0.13% blood components). Recommended HDL over 40 mg / dl. Many professionals believe that the ratio of total cholesterol / HDL is more important to assess the general health HDL and LDL numbers only. Total cholesterol is generally accepted to be less than 200 mg / dl for healthy person. In general, total cholesterol / HDL is considered healthy is less than 4 (eg 160 mg / dl and cholesterol 40 mg / dl HDL).
Although fats such as cholesterol serve important structural functions and hormones, what about fats that are used for energy use? They are known as triglycerides, have a different structure and functions as cholesterol. They consist of three fatty acid chains linked to a small molecule called glycerol. Gram for gram, the fatty acids are twice as much energy than protein or carbohydrates. The triglyceride level in normal blood is less than 150 mg / dl. There are four main types of fats that come from food. The Saturated fats are usually animal derived. They tend to increase LDL levels. Monounsaturated fats like olive plants and peanuts. They help fight cholesterol and oxidation (4). Polyunsaturated fats is mainly derived from plants. Help reduce total cholesterol and LDL. Unfortunately, like cholesterol, polyunsaturated fatty acids are easily oxidized. Linseed oil is a good example of polyunsaturated fats. Trans fats are artificially to help consolidate for convenience. Margerine is a good example of Trans fat. No trans fats only increase LDL cholesterol levels and also lower HDL (4).
There are many different factors that can influence cholesterol. When ingested carbohydrate carbon, the hormone insulin is released into the blood. Insulin increases then the production of cholesterol (5). Stress can also increase cholesterol production, because cholesterol is stress hormones (1). In fact, as mentioned earlier, cholesterol is the cornerstone of all steroid hormones (5). Unfortunately, cholesterol is the only not the only factor that determines the health of a person's arteries are. When minerals and antioxidant vitamins are low, the cholesterol can be used as an antioxidant in the blood (1). Oxidized cholesterol has been sacrificed to neutralize damaging free radical molecules. But the situation inside the body Even worse, because the oxidized cholesterol, and finally join the artery walls. Immune cells try to clean damaged cholesterol, but they eventually die and sticking to the arterial wall as well. The above process then progresses to atherosclerosis (heart disease). The above explanation about the dangers of cholesterol Rusty is another reason to supplement with antioxidants.
Force medical recommendations is to keep the total cholesterol level below 200 mg / dl. However, the association between high cholesterol and death is not apparent until the level is above 240 mg / dl. mg Therefore, the level of 200 mg / dl, 240 dl / is often called borderline high cholesterol (4). There is some controversy regarding the use of cholesterol-lowering drugs, because the levels of cholesterol can be dangerous if they fall too low (6). Some experts do not agree that high cholesterol should be blamed for heart attacks. The blood level of cholesterol through a cardiac patient is 244 mg / dl. Only 20% more than the rate of cholesterol the average American, which is 205 (7). Furthermore, one of the three victims of heart attacks have levels cholesterol below 200 mg / dl (8).
Niacin (vitamin B3) has been used both clinical and holistic approach to lowering cholesterol. The amount of niacin to achieve is very high, more than 1000 mg per day (the average B-complex supplement of only 50 mg). Although niacin is a natural vitamin and high may have several side effects. These may include liver damage, muscle problems, eye problems, heart disorders, glucose intolerance, and peptic ulcers (9). Vitamin C may reduce cholesterol levels (10). Nobel Prize winning scientist Linus Pauling twice noted that vitamin C may help heart health in two complementary ways: by strengthening the walls of the arteries, and the conversion of cholesterol to bile acids, which in turn helps in the digestion of metabolism of fats and downstream (10).
At this time there is a controversy about vitamin E. In theory, should be taken to ensure that capacity of fat-soluble antioxidants to protect the rate of cholesterol in the blood. In fact, high doses of vitamin E (400 IU / day or more) may actually increase mortality in a small percentage of unknown mechanisms (11). Supplements of vitamin E are usually as a simple, alpha-tocopherol. In nature, such as vitamin E are four main forms, alpha, beta, gamma and delta tocopherols. Taking too much alpha-tocopherol can inhibit the absorption and action of three other species of vitamin E. If someone decides to supplement with vitamin E, make sure it is natural and contains the four forms of the vitamin. Moreover, in these ten studies have shown vitamin E to be dangerous (11), five studies have been conducted in patients who had already established diseases that are serious, and can not be avoided by taking more than a vitamin. Eight out of ten studies also had a mean age of patients in the study over sixty years, which means that most of them have accumulated oxidative damage in body for several decades before any anti-oxidant treatment was initiated. For now, if you choose a vitamin E supplement, take only 200 IU / day of mixed tocopherols, unless otherwise by your doctor.
A number of cholesterol drugs on the market. Here is the list of potential side effects of these drugs.
Statins (cholesterol production by category)
(Lescol), simvastatin (Zocor) pravastatin (Pravachol), lovastatin (Mevacor)
Muscle and liver problems for all statins. Mevacor fat also increases inflammatory
Fibric acids (the production of cholesterol by category)
Gemfibrozil (Lopid), fenofibrate (Tricor)
problems gallbladder, liver and kidney toxicity
Bile acid sequestrants (cholesterol in the blood below)
Cholestyramine (Questran), colestipol (Colestid), Colesevlam (Welchol)
All non-chelating relatively safe as safe Questran Children
Here are some possible side effects natural supplements to lower cholesterol and herbs:
Guggulipids, Commiphora Mukul myrrh extract herb: May cause hypoglycemia
Garlic: allergic reactions, bleeding, multiple drug interactions and Garlic
The grains and yeast
extract of red yeast rice, contains the active ingredient lovastatin, despite the toxicity of lovastatin above
Chromium picolinate: Possible mild hypoglycaemia
Guar gum, Rare cases of hypoglycemia
Oats: triglycerides installation times
Apple Pectin: relatively safe, can reduce levels of certain drugs in the body
L-Carnitine: Rare cases of seizures
There are some interesting facts about how to regulate the levels of cholesterol: high fiber diets are one of the best ways to help regulate blood cholesterol (1). Too much coffee (number cups a day) can raise cholesterol. Cook with extra virgin olive oil is beneficial for people with high cholesterol. There are many ways to help maintain levels A person's cholesterol in a healthy range by natural means. You can explore various natural slopes treat hypercholesterolemia, lest they take the path of pharmaceutical drugs.
1. Erasmus U. Fats that heal, fats that kill, 14th ed. Burnaby, British Columbia (Canada): Books Alive, 1993.
2. Balch, P. nutrition prescription Healing, 3rd ed. Avery Books / Penguin Putnam Inc., 2000.
3. , R., & Monte, T. Fleming Stop Inflammation Now! New York, NY: Putnam, 2004.
4. Lithia, S. ed. Clinic Mayo Family Health Book, 3rd ed. New York, NY: Harper Collins Books, 2003.
5. Sears, Area B. New York, NY: Regan Books / HarperCollins Publishers, 1995.
6. Eades, M., & Eades, M. Power Life Plan of the protein. New York, NY: Warner Books, 2000.
7. Physicians Committee for Responsible Medicine manuscript — (orig. in Italian), published online 17/12/2000.
8. Feinstein, A. vitamins cure. Emmaus, PA: Rodale Books, Inc., 1996.
9. PDR Generics, 3rd ed. Montvale, New Jersey: Medical Economics Company, Inc., 1997.
10. Pauling, L. (1974). It is the recommended daily allowance of vitamin C adequate? Minutes National Assembly Academy of Sciences, 71 (11): 4442-4446.
11. Miller, ER, et al. Al (2005). Meta-analysis: High doses of vitamin E supplementation may increase all cause mortality. Annals of Internal Medicine, 142 (1) 1-11.
About the Author
Dr. Jensen is both a consultant and author in the BioMedical and Nutrition fields. He has previously written a book on both topics, The Failures of American Medicine, published in 2002. Dr. Jensen has also written a doctoral dissertation on how Vitamin C can reduce stress and allergies via its antihistamine effect. He has worked in a broad range of BioMedical fields, such as gene regulation, cancer research, and HIV vaccine development. However, Dr. Jensen eventually decided that helping people more directly would be more rewarding for everyone involved. He has since helped clients with dozens of different ailments. Dr. Jensen is a practitioner in the field of Metabolic Typing, which characterizes different biochemistries among people based on certain physical and behavioral traits they have.
You can contact Dr. Jensen at 1-800-390-5365, or mail him at email@example.com.